
Thermo Fisher Scientific Phospho-HNF4A (Ser313) Polyclonal Antibody
HNF4A 단백질의 Ser313 인산화 부위를 인식하는 폴리클로날 항체. Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human HNF4 alpha around the phosphorylation site of Serine 313 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553783 |
Product Specific Information
- Detects endogenous HNF4A protein at approximately 52 kDa.
- Purity: >95% by SDS-PAGE.
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4A) is an orphan nuclear receptor expressed in the liver, kidney, intestine, and pancreas.
Mutations in HNF4A are associated with maturity-onset diabetes of the young type 1 (MODY1).
HNF4A binds DNA as a homodimer, and the gene can produce up to nine isoforms (HNF4A1–HNF4A9) through alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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