Thermo Fisher Scientific TCL1A Polyclonal Antibody
TCL1A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the amino-terminal sequence of human TCL1 (UniProt ID: P56279-1, antigen length: 114 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 60 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979677 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, where chromosomal rearrangements bring the TCL1 gene close to T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements. In normal T cells, TCL1 is expressed in CD4-/CD8- cells, but not in later differentiation stages. TCL1 functions as a coactivator of the cell survival kinase AKT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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