Thermo Fisher Scientific CABYR Polyclonal Antibody
CABYR 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간, 생쥐, 랫트 시료에서 반응하며, Affinity chromatography로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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- PA5103683
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Thermo Fisher Scientific CABYR Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CABYR (Accession O75952), corresponding to amino acid residues E310–V360 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853016 |
Product Specific Information
This antibody detects endogenous levels of total CABYR.
Target Information
Spermatozoa gain fertilization capacitation and hyperactivation after residing in the uterus or oviduct. Calcium, cAMP, and protein tyrosine phosphorylation are necessary for the molecular mechanisms that allow for this transformation.
CABYR (Calcium-binding tyrosine phosphorylation-regulated protein), also known as Fibrousheathin-2 or Cancer/testis antigen 88, is a 493-amino-acid protein expressed in sperm flagella and exhibits increased tyrosine phosphorylation during capacitation.
There are six named isoforms of CABYR produced by alternative splicing events:
- Isoform 1: expressed in testis
- Isoform 3 and 5: expressed in pancreas, brain, and various brain tumors
- Isoforms 1, 2, and 6: likely bind calcium
- Isoforms 3, 4, and 5: probably do not bind calcium
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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