Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Thr183, Tyr185, Thr221, Tyr223) Recombinant Rabbit Monoclonal Antibody (6F10V6)
Phospho-JNK1/2/3 (Thr183, Tyr185, Thr221, Tyr223)을 인식하는 재조합 토끼 단클론 항체. WB, IHC, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 발현, 고순도 친화 크로마토그래피 정제. -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6F10V6 |
| Immunogen | A synthetic phosphorylated peptide around T183 of human MAPK8 (NP_620637.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.09 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094419 |
Product Specific Information
Immunogen sequence: GLARTAGTSF MMTPYVVTRY YRAPEVI
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are serine-threonine protein kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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