Thermo Fisher Scientific SHP2 Recombinant Rabbit Monoclonal Antibody (6G11)
SHP2 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. HEK293 세포 발현 시스템을 사용하며, 고순도 친화 크로마토그래피 정제 제품입니다. PBS 기반 저장용액으로 안정적 보관 가능하며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:5,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6G11 |
| Immunogen | A synthesized peptide derived from human SHP2 (aa 15–28) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898263 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains, functioning as phospho-tyrosine binding domains that mediate substrate interactions.
It is widely expressed and plays a regulatory role in diverse signaling events such as mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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