Thermo Fisher Scientific CD51 Recombinant Rabbit Monoclonal Antibody (5G3)
Thermo Fisher Scientific의 CD51(Integrin αV) 재조합 토끼 단클론 항체(5G3)는 Western blot 및 IHC(P) 분석에 적합합니다. 인간 시료에 반응하며, HEK293 세포에서 발현된 IgG 형식의 비접합 항체입니다. 높은 특이성과 재현성을 제공하며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5G3 |
| Immunogen | A synthesized peptide derived from human Integrin alpha V |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898259 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins.
Among the known associating beta chains (β1, β3, β5, β6, and β8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands. The αVβ3 integrin, often referred to as the Vitronectin receptor (VNR), is one of the most studied. Beyond adhesion, many integrins are known to facilitate signal transduction.
Integrin β3 is found along with the αIIb chain in platelets. Integrins are involved in cell adhesion and cell-surface mediated signaling.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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