Thermo Fisher Scientific CNTFR Polyclonal Antibody
Thermo Fisher Scientific의 CNTFR Polyclonal Antibody는 마우스 CNTFR 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공되고 -20°C에서 보관합니다. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CRSNTYPKGFY) corresponding to the internal amino acids of CNTFR (aa 116–127) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977725 |
Product Specific Information
- This antibody is predicted to react with canine, human, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
This gene encodes a hematopoietin/interferon-class receptor belonging to the cytokine superfamily. The CNTFR gene product represents the CNTF-specific alpha subunit of a heterotrimeric receptor complex, which also includes LIFR and gp130. The receptor is membrane-bound via a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires CNTF binding to this alpha component, enabling recruitment of gp130 and LIFR beta to form the tripartite complex. This signaling promotes gene expression, cell survival, and differentiation in various neuronal cell types. Alternative splicing produces two variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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