Thermo Fisher Scientific GnRHR Polyclonal Antibody
GnRHR 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체로, Western blot에 사용 가능. 인공 펩타이드 면역원 기반 제작. 인간 및 개에서 반응 예측. 고순도 액상 형태로, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QKWTQKKEKGK) corresponding to internal amino acids of GNRHR (aa 61–72) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10975407 |
Product Specific Information
- Predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
This gene encodes the receptor for type 1 gonadotropin-releasing hormone (GnRHR).
The receptor is part of the seven-transmembrane G-protein coupled receptor (GPCR) family and is expressed on pituitary gonadotrope cells, lymphocytes, breast, ovary, and prostate.
Upon ligand binding, the receptor activates a phosphatidylinositol-calcium second messenger system, leading to the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Defects in this gene can cause hypogonadotropic hypogonadism (HH).
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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