
Thermo Fisher Scientific TrkA Polyclonal Antibody
Rabbit polyclonal antibody targeting TrkA (NTRK1) for WB and IHC applications. Recognizes extracellular domain of rat TrkA. Lyophilized form, reconstitute with sterile water. Suitable for neurobiology and signaling research.
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Thermo Fisher Scientific TrkA Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the extracellular domain of rat TrkA |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10709604 |
Product Specific Information
- Reconstitute using 100 µL of sterile water.
- Glycerol (1:1) may be added for additional stability.
Target Information
NTRK1 (TRKA) belongs to the neurotrophic factor family central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Its presence promotes cell differentiation and may specify sensory neuron subtypes. Mutations in TrkA have been linked to congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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