Thermo Fisher Scientific Phospho-NACA (Ser43) Polyclonal Antibody
인간 NACA 단백질의 Ser43 인산화 부위에 특이적인 Rabbit Polyclonal Antibody. Western blot에 적합하며, 고순도 액상 형태로 제공. 연구용으로만 사용 가능하며 -20°C에서 보관.
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Thermo Fisher Scientific Phospho-NACA (Ser43) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NACA around the phosphorylation site of Ser43 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817414 |
Target Information
NACA prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). It binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. NACA also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites), and may act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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