Thermo Fisher Scientific Laforin Polyclonal Antibody
Laforin 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot 및 IHC에 적합. Human과 Mouse에 반응하며, 합성 펩타이드 항원을 사용. 연구용으로만 사용 가능하며, 안정적 보관을 위해 -20°C 저장 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 50–100 of mouse Laforin conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in human.
- Specificity of this antibody: Laforin.
Target Information
The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes.
Mutations in this gene are associated with myoclonic epilepsy of Lafora.
EPM2A interacts with several proteins involved in glycogen metabolism and exhibits robust phosphatase activity against phosphorylated complex carbohydrates, suggesting a role in glycogen metabolism regulation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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(이미지 파일명: OSL00023W-100UL_EPM2A_Q9WUA5-1_Rabbit.svg, OSL00023W-100UL_EPM2A_Q9WUA5-1_Rabbit_PDP.jpeg)
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