Thermo Fisher Scientific L3MBTL1 Polyclonal Antibody
인간 L3MBTL1 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot과 IHC에 적합하며, 비결합형 동결건조 형태로 제공됩니다. 장기 보관 시 -20°C에서 안정적이며 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 550–600 of human L3MBTL1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: L3MBTL1.
Target Information
L3MBTL1 is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain.
It is localized to condensed chromosomes in mitotic cells, and overexpression in a glioma cell line results in improper nuclear segregation and cytokinesis, producing multinucleated cells.
L3MBTL1 represents a polycomb group gene; its encoded protein regulates gene activity, likely via chromatin modification.
Polycomb group protein specifically recognizes and binds mono- and dimethyllysine residues on target proteins, acting as a reader of post-translational modifications.
Alternatively spliced transcript variants encoding different isoforms of the L3MBTL1 gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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