Thermo Fisher Scientific CD140a (PDGFRA) Recombinant Rabbit Monoclonal Antibody (BLR078G)
Recombinant rabbit monoclonal antibody targeting human PDGFRA (CD140a). Validated for WB, ICC/IF, and IP applications. High purity, unconjugated form with 0.25 mg/mL concentration. Recommended for research use in cell signaling and receptor studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 20 µL/1 mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR078G |
| Immunogen | Recombinant protein representing the extracellular domain of human Platelet Derived Growth Factor Receptor Alpha (residues 24–525) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2926477 |
Product Specific Information
Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE cell sections.
Target Information
PDGFRA is a cell surface receptor tyrosine kinase that binds members of the platelet-derived growth factor family. These growth factors act as mitogens for cells of mesenchymal origin. The specific growth factor bound to a receptor monomer determines whether the receptor forms a homodimer or heterodimer, composed of both PDGFRA and PDGFRB polypeptides. Knockout mouse studies indicate that PDGFRA is critical for kidney development, as heterozygous mice exhibit defective kidney phenotypes.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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