Thermo Fisher Scientific CDT1 Recombinant Rabbit Monoclonal Antibody (23GB5790)
CDT1 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot에 최적화되어 있습니다. HEK293F 시스템에서 발현되며, 높은 특이성과 재현성을 제공합니다. PBS/glycerol 완충액에 보관되며 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5790 |
| Immunogen | A synthesized peptide derived from human CDT1 (230–546 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis. It functions as a catalytic subunit of the MLL1/MLL complex, mediating methylation of Lys-4 of histone H3 (H3K4me) and acetylation of Lys-16 of histone H4 (H4K16ac). KMT2A specifically mediates H3K4 methylation, a marker for epigenetic transcriptional activation. It requires other components of the MLL1/MLL complex for full enzymatic activity and is involved in the transcriptional activation of HOXA9 and PPP1R15A-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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