Thermo Fisher Scientific NACA Polyclonal Antibody
인간 NACA 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었고, PBS와 50% 글리세롤에 보관됩니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NACA (Accession Q13765), corresponding to amino acid residues T27–A54 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900247 |
Product Specific Information
Antibody detects endogenous levels of total NACA.
Target Information
NACA prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). It binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER.
NACA also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites), and may act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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