Thermo Fisher Scientific MAD3 Polyclonal Antibody
Thermo Fisher Scientific의 MAD3 Polyclonal Antibody는 Western blot 및 IHC에 적합한 토끼 유래 다클론 항체입니다. Mouse와 Rat 시료에 반응하며, 내부 영역 합성 펩타이드를 면역원으로 사용했습니다. 연구용으로 세포 증식 및 종양 관련 단백질 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from internal region of mouse MAD3 (Max dimerization protein 3) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: MAD3.
Target Information
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators.
The encoded protein forms a heterodimer with the cofactor MAX, which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription.
Disruption of the MAX–MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis.
Transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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