Thermo Fisher Scientific IFITM3 Polyclonal Antibody
IFITM3 단백질 검출용 토끼 폴리클로날 항체로, WB 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간, 마우스, 랫트에 반응합니다. 고순도(>95%) 항체로, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 9–54 of Human IFITM3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719252 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM family. These proteins are induced by type I and type II interferons and contain interferon-stimulated response elements (ISREs) in their promoter regions.
IFITM proteins play roles in cellular anti-proliferative activities, homotypic cell adhesion, and are often upregulated in cancer cells, suggesting a role in carcinogenesis.
IFITM3 is a 133 amino acid membrane protein induced by IFN-alpha and IFN-gamma, and its expression can be regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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