Thermo Fisher Scientific Transthyretin (Prealbumin) Monoclonal Antibody (TTR/4292)
Transthyretin(Prealbumin)을 인식하는 Mouse Monoclonal Antibody로 Western blot, IHC 등 다양한 응용에 사용 가능. Human 시료에 반응하며, Protein A/G로 정제된 1 mg/mL 액상 형태. PBS(pH 7.4) 버퍼, 보존제 없음, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TTR/4292 |
| Immunogen | Recombinant human full-length Transthyretin (amino acids 1–147, UniProt ID: P02766-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transthyretin (TTR), commonly known as prealbumin, is a plasma protein that functions as a transporter for thyroxine and retinol-binding protein. It is primarily synthesized in the liver and secreted into the plasma. TTR constitutes approximately 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the central nervous system. Transthyretin is associated with neuritic plaques, neurofibrillary tangles, and microangiopathic lesions in senile cerebral amyloid. Over 40 mutations in the TTR gene have been linked to amyloid deposition disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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