Thermo Fisher Scientific TNFSF15 Monoclonal Antibody (3H1)
TNFSF15 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse monoclonal 항체입니다. Western blot 및 ELISA에 적합하며, 인간 시료에 반응합니다. Affinity chromatography로 정제되었으며, PBS(pH 7.4)에 보존제 없이 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H1 |
| Immunogen | TNFSF15 (AAH74941.1, 72 a.a. – approx. 251 a.a.) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV VRQTPTQHFK NQFPALHWEH ELGLAFTKNR MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLL
Target Information
The protein encoded by this gene is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is abundantly expressed in endothelial cells but not in B or T cells. Expression is inducible by TNF and IL-1α. This cytokine acts as a ligand for receptors TNFRSF25 and TNFRSF21/DR6, activating NF-kappaB and MAP kinases, and functions as an autocrine factor inducing apoptosis in endothelial cells. It also inhibits endothelial cell proliferation, potentially functioning as an angiogenesis inhibitor. An additional isoform from an alternatively spliced transcript variant has been reported, though its sequence is undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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