Thermo Fisher Scientific TLR11 Polyclonal Antibody, FITC
TLR11 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Flow Cytometry에 적합합니다. Mouse와 Rat 반응성을 가지며 Rabbit IgG로 제작되었습니다. 단백질 G로 정제되어 4°C 암소 저장 조건을 권장합니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (amino acids 911–926) of TLR11 protein |
| Conjugate | FITC (Fluorescein) |
| Excitation/Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Protein G |
| Storage Buffer | 50 mM sodium borate |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540630 |
Target Information
The Toll-like receptor (TLR) family in mammals comprises transmembrane proteins characterized by multiple leucine-rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. TLRs signal through adaptor molecules and are key mediators of innate immunity essential for microbial recognition.
TLR11 specifically responds to uropathogenic bacteria rather than known TLR ligands. TLR11-deficient mice are highly susceptible to kidney infections caused by uropathogenic bacteria, suggesting a protective role of TLR11 in the urogenital system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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