Thermo Fisher Scientific BDKRB1 Polyclonal Antibody
Rabbit polyclonal antibody against human BDKRB1. Validated for WB and IHC applications. Lyophilized form, reconstitutable in sterile water. Suitable for inflammation and receptor signaling studies. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human BDKRB1 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: BDKRB1.
Target Information
Bradykinin, a 9 amino acid peptide, is generated under pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors bind bradykinin and mediate responses to these conditions. The protein encoded by the BDKRB1 gene is synthesized de novo following tissue injury. Receptor binding increases cytosolic calcium ion concentration, leading to chronic and acute inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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