Thermo Fisher Scientific COX6B2 Polyclonal Antibody
COX6B2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 IHC(P) 실험에 적합합니다. 사람 및 생쥐 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COX6B2 (Accession Q6YFQ2), corresponding to amino acid residues M1–R41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818743 |
Product Specific Information
Antibody detects endogenous levels of total COX6B2.
Target Information
The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some nuclear.
Localized to the intermembrane space, COX6B2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is an 88 amino acid mitochondrial protein responsible for joining the two COX monomers to form the COX dimer.
COX6B2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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