Thermo Fisher Scientific WARS Polyclonal Antibody
Rabbit polyclonal antibody targeting human WARS (Tryptophanyl-tRNA synthetase). Validated for WB, IHC, IHC-P, and IP applications. Supplied as liquid, unconjugated, 1 mg/mL concentration. Recommended storage at 4°C with 1-year shelf life.
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Thermo Fisher Scientific WARS Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 421–471 of Human Tryptophanyl-tRNA Synthetase (WARS, UniProt ID: P23381-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution.
Two forms of tryptophanyl-tRNA synthetase exist: a cytoplasmic form (WARS) and a mitochondrial form (WARS2). WARS catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. It belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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