
Thermo Fisher Scientific AP2 alpha Polyclonal Antibody
Rabbit polyclonal antibody against Human AP2 alpha for WB and IP applications. Recognizes TFAP2A transcription factor involved in development and gene regulation. Supplied unconjugated in liquid form, 0.64 mg/mL concentration. Suitable for HeLa and Rat...
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunoprecipitation (IP)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 236–437 of Human AP2 alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.64 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547243 |
Product Specific Information
- Recommended positive controls: HeLa, C8D30, Rat2
- Predicted reactivity: Mouse (98%), Rat (99%), Zebrafish (87%), Xenopus laevis (93%), Chicken (98%), Sheep (99%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.
AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in diverse biological functions, including development of the eye, face, body wall, limbs, and neural tube.
They also suppress genes such as MCAM/MUC18, C/EBP alpha, and MYC.
TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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