Thermo Fisher Scientific SULT1A1 Polyclonal Antibody
SULT1A1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, IP에 사용 가능. Human에 반응하며 HepG2 세포에서 양성 대조로 권장. 항원 친화 크로마토그래피로 정제된 액상 형태로, 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA529766
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–196 of Human SULT1A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547240 |
Product Specific Information
- Recommended positive control: HepG2
- Predicted reactivity: Rat (81%), Dog (87%), Bovine (86%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, activation of procarcinogens, and regulation of hormones by catalyzing sulfate conjugation of these substances. Members of the SULT1, SULT2, and SULT3 groups show selectivity toward specific substrates.
SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid cytoplasmic protein belonging to the sulfotransferase family. It functions as a homodimer expressed in brain, liver, skin, and lung tissue, catalyzing the sulfate conjugation of catecholamines, phenolic drugs, and neurotransmitters. Through this activity, SULT1A1 aids in the elimination of various compounds and may play a role in the activation of carcinogenic N-hydroxyarylamines, suggesting possible involvement in carcinogenesis.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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