Thermo Fisher Scientific RanBP8 Polyclonal Antibody
RanBP8 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 사용 가능. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태, 1 mg/mL 농도, 4°C 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 987 and 1037 of Human RAN binding protein 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Importin 8 is a 1037 amino acid nuclear protein with a RAN binding site. It belongs to the RAN-binding protein superfamily and shares an N-terminal sequence motif with importin-beta that accounts for RAN GTP binding. It binds to the nuclear pore complex (NPC) and functions as a transport carrier mediating nuclear import of ribosomal proteins with a classical nuclear localization signal. Importin 8, along with RANGTP and RANBP1, inhibits the GAP stimulation of the RAN GTPase and also assists in the nuclear import of SRP19 with transportin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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