Thermo Fisher Scientific C5AR1 Monoclonal Antibody (8D6), PE
인간 C5a 수용체(CD88)를 표적하는 PE 결합 단클론 항체로, 유세포 분석(FACS)에 적합합니다. Rat IgG2a 아이소타입이며, 단백질 G 정제 및 BSA 함유 PBS 용액 형태로 제공됩니다. 565/576 nm 형광 특성을 가지며 연구용으로 사용됩니다.
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Thermo Fisher Scientific C5AR1 Monoclonal Antibody (8D6), PE
Applications
- Flow Cytometry (FACS)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8D6 |
| Immunogen | RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539132 |
Additional Formats
- Unconjugated (MA1-70060)
- Biotin (MA5-17740)
- FITC (MA5-17741)
- Custom conjugation available upon request
Product Specific Information
MA5-17742 targets C5a receptor/CD88 in FACS applications and shows reactivity with human samples.
The immunogen is RBL-2H3 cells transfected to express human C5aR on the surface.
Target Information
CD88 (C5aR1) is a C5a Anaphylatoxin Receptor mediating effects of potent chemotactic agents. It is implicated in asthma and expressed in various tissues including myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract.
CD88 stimulates chemotaxis, granule enzyme release, and superoxide anion production. It is part of the classical complement cascade and may contribute to tissue injury associated with ischemia or sepsis.
Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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