Thermo Fisher Scientific C5AR1 Monoclonal Antibody (8D6), Biotin

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1.0 µg/1x10^6 cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

8D6

Immunogen

RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface

Conjugate

Biotin Biotin Biotin

View additional formats

• Unconjugated
• FITC
• PE
• Request custom conjugation

Form

Liquid

Concentration

0.1 mg/mL

Purification

Protein G

Storage buffer

PBS with 4-5mg/mL BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2539130

Product Specific Information

MA5-17740 targets C5a receptor/CD88 in FACS applications and shows reactivity with Human samples.

The MA5-17740 immunogen is rBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface.

Target Information

CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production. CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.