Thermo Fisher Scientific SIN3A Polyclonal Antibody
SIN3A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF, IP, ChIP 등 다양한 연구 응용에 적합. Human 및 Mouse 시료에 반응하며, 고순도 항원 친화 크로마토그래피로 정제된 액상 형태.
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Thermo Fisher Scientific SIN3A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5 µg/mL | View 6 publications |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:500 | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | - |
| ChIP assay (ChIP) | 1–3 µL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues M(1) K R R L D D Q E S P V Y A A Q Q R R(19) of mouse mSin3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2187625 |
Product Specific Information
PA1-870 detects mSin3A from human and mouse tissues and cells.
It has been successfully used in Western blot, ICC/IF, ChIP, IHC-P, and immunoprecipitation procedures.
By Western blot, this antibody detects an ~150 kDa protein representing mSin3A from T47D cell extract.
The immunogen is a synthetic peptide corresponding to residues M(1) K R R L D D Q E S P V Y A A Q Q R R(19) of mouse mSin3A.
Target Information
Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes.
There are two mammalian isoforms, mSin3A and mSin3B.
Containing four paired amphipathic helix domains (PAH domains), mSin3A and mSin3B directly interact with transcriptional repressor proteins such as HDAC1, HDAC2, RbAp46, MeCP2, Mad/Max heterodimer, SMRT, and N-CoR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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