Thermo Fisher Scientific GPHN Monoclonal Antibody (OTI2C2), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high-affinity binding to receptor subunit domains and tubulin dimers.
In nonneuronal tissues, this protein is also required for molybdenum cofactor biosynthesis.
Mutations in the gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Multiple alternatively spliced transcript variants encoding different isoforms have been described, though the full-length nature of all variants is not fully known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.