Thermo Fisher Scientific GPHN Monoclonal Antibody (OTI2C2), TrueMAB
인간 GPHN 단백질을 인식하는 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로 신경세포 수용체 앵커 단백질 분석에 유용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C2 |
| Immunogen | Full length human recombinant protein of human GPHN produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high-affinity binding to receptor subunit domains and tubulin dimers.
In nonneuronal tissues, this protein is also required for molybdenum cofactor biosynthesis.
Mutations in the gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Multiple alternatively spliced transcript variants encoding different isoforms have been described, though the full-length nature of all variants is not fully known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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