Thermo Fisher Scientific PDCD10 Polyclonal Antibody, DyLight 488
PDCD10 단백질을 인식하는 DyLight 488 결합 토끼 폴리클로날 항체. 인간 시료에 반응하며 세포사 및 혈관 발달 관련 연구에 활용. 항원 친화 크로마토그래피로 정제, 형광 분석에 적합. 4°C 암소 보관, 동결 금지.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–3 µg/1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human PDCD10 recombinant protein (Position: M1–A212) |
| Conjugate | DyLight™ 488 |
| Excitation / Emission Max | 492 / 519 nm |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746907 |
Target Information
This gene encodes an evolutionarily conserved protein associated with cell apoptosis.
The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway.
It also interacts with and is phosphorylated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular development.
Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages.
Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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