Thermo Fisher Scientific PCSK9 Monoclonal Antibody (410420)
인간 PCSK9 단백질을 특이적으로 인식하는 Mouse IgG1 단클론 항체. Western blot 및 Immunoprecipitation에 적합. 교차 반응 없음. Lyophilized 형태로 제공되며 PBS + trehalose buffer에 재구성 가능. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 410420 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Proprotein Convertase 9 (PCSK9) isoform 1 Arg29–Gln692 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606593 |
Product Specific Information
This antibody detects the mature form of human Proprotein Convertase 9 (PCSK9) in direct ELISAs and Western blots.
It does not cross-react with recombinant human PCSK1, PCSK7, or recombinant mouse PCSK9.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family.
It is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum.
PCSK9 plays a key role in cholesterol homeostasis and may contribute to cortical neuron differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-24149_PCSK9_Q8NBP7-1_House_mouse.svg, MA5-24149_PCSK9_Q8NBP7-1_House_mouse_PDP.jpeg)
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