Thermo Fisher Scientific PCSK9 Monoclonal Antibody (410420)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunoprecipitation (IP)

25 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

410420

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Proprotein Convertase 9/PCSK9 isoform 1 Arg29-Gln692 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCSK9,uniProtId:Q8NBP7-1,ncbiNodeId:9606,antigenRange:29-692,antigenLength:692,antigenImageFileName:MA5-24149_PCSK9_Q8NBP7-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24149_PCSK9_Q8NBP7-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606593

Product Specific Information

This antibody detects the mature form of human Proprotein Convertase 9/PCSK9 in direct ELISAs and Western blots. This antibody does not cross-react with recombinant human (rh) PCSK1, rhPCSK7, or recombinant mouse PCSK9.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.