Thermo Fisher Scientific H3K14ac Polyclonal Antibody
H3K14ac 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, 액상 형태로 제공됩니다. 고순도 친화성 크로마토그래피 정제, 안정적인 PBS/glycerol 저장 버퍼 포함.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic acetylated peptide around K14 of human H3 (NP_0035201) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.28 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914654 |
Product Specific Information
- Positive test controls include: HeLa, NIH/3T3, C6
- Target location: Chromosome, Nucleus
- Immunogen sequence: GGKAP
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the nucleosome structure. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones influence chromatin structure and transcription factor binding. The N-terminal tail of histone H3 can undergo methylation, acetylation, or phosphorylation on lysine, arginine, serine, or threonine residues, affecting cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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