Thermo Fisher Scientific H4R3me2a Polyclonal Antibody
H4R3me2a에 특이적인 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ELISA 등 다양한 응용에 적합하며 고순도 Affinity Chromatography로 정제되었습니다. 안정적인 PBS/glycerol buffer 포맷으로 -20°C 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic asymmetric dimethylated peptide around R3 of human HIST2H4A (NP_0035291) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914656 |
Product Specific Information
- Positive test controls: HeLa
- Target location: Chromosome, Nucleus
- Immunogen sequence: SGRGK
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction.
This gene is intronless and encodes a member of the histone H4 family. Transcripts lack polyA tails and contain a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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