Thermo Fisher Scientific NGF Receptor Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 273-427 of human p75NTR/NGFR (NP_0024981) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NGFR (CD271),uniProtId:P08138-1,ncbiNodeId:9606,antigenRange:273-427,antigenLength:427,antigenImageFileName:PA5-88087_NGFR_CD271_P08138-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88087_NGFR_CD271_P08138-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.59 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804640

Product Specific Information

Positive Samples: SH-SY5Y, Mouse testis, Rat brain; Cellular Location: Membrane, Single-pass type I membrane protein

Immunogen sequence: KRWNSCKQNK QGANSRPVNQ TPPPEGEKLH SDSGISVDSQ SLHDQQPHTQ TASGQALKGD GGLYSSLPPA KREEVEKLLN GSAGDTWRHL AGELGYQPEH IDSFTHEACP VRALLASWAT QDSATLDALL AALRRIQRAD LVESLCSEST ATSPV

Target Information

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.