Thermo Fisher Scientific CD16 Polyclonal Antibody
CD16 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응. Western blot 및 ELISA에 최적화된 고순도 항체. 세포막 및 분비형 단백질 검출에 적합하며, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 150–250 of human FCGR3A (NP_000560.7) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.22 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914393 |
Product Specific Information
Positive test controls include: LO2, Mouse liver, Rat liver.
Target localization: Cell membrane, Secreted, Single-pass type I membrane protein.
Immunogen sequence:
YFHHNSDFYI PKATLKDSGS YFCRGLFGSK NVSSETVNIT ITQGLAVSTI SSFFPPGYQV SFCLVMVLLF AVDTGLYFSV KTNIRSSTRD WKDHKFKWRK D
Target Information
CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and plays a role in immune complex clearance, antibody-dependent cellular cytotoxicity, and viral infection enhancement.
FCGR3A shares high similarity with FCGR3B located on chromosome 1.
- Expression: NK cells (membrane glycoprotein)
- FCGR3B Expression: PMN cells (PI-anchored)
Mutations in FCGR3A are associated with Immunodeficiency 20, Herpes Zoster, and susceptibility to lupus erythematosus and recurrent viral infections.
Alternative splicing generates multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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