Thermo Fisher Scientific FOLR2 Monoclonal Antibody (OTI8G1), TrueMAB
인간 FOLR2 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot 및 IHC(P) 분석에 적합. 무보존제, 동결건조 형태로 제공되며 PBS 및 trehalose 버퍼에 안정적. 연구용으로만 사용 가능.
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Thermo Fisher Scientific FOLR2 Monoclonal Antibody (OTI8G1), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC(P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–221 of human FOLR2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FOLR2 belongs to the folate receptor (FOLR) family, clustered on chromosome 11. These receptors have high affinity for folic acid and reduced derivatives, mediating delivery of 5-methyltetrahydrofolate into cells.
FOLR2 shares 68% sequence homology with FOLR1 and 79% with FOLR3. Initially considered placenta-specific, it is also expressed in other tissues and may be involved in methotrexate transport in synovial macrophages of rheumatoid arthritis patients.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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