Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI8G5), TrueMAB
Human CSF2 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot 및 IHC(P) 분석에 적합. 고순도 친화 크로마토그래피 정제, 보존제 무첨가. 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–144 of human CSF2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form is a homodimer found in the extracellular space.
This gene is located in a cluster on chromosome region 5q31, associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia.
The cluster also includes IL4, IL5, and IL13 genes. GM-CSF is involved in promoting tissue inflammation, and elevated cytokine levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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