Thermo Fisher Scientific MKL1 Monoclonal Antibody (OTI3C8), TrueMAB
인간 MKL1 단백질(aa 165-397)을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합. 동결건조 형태로 제공되며 PBS + trehalose buffer에 재구성 가능. 연구용으로 세포핵 신호 전달 및 근육세포 분화 관련 연구에 활용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C8 |
| Immunogen | Human recombinant protein fragment (aa 165–397 of human MKL1) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The MKL1 gene encodes a protein that interacts with myocardin, a transcription factor regulating smooth muscle cell differentiation. This nuclear protein helps transduce signals from the cytoskeleton to the nucleus. A translocation involving MKL1 and the RNA-binding motif protein-15 gene has been linked to acute megakaryocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본 이미지 파일: CF805225_MKL1_Q969V6-1_House_mouse.svg, CF805225_MKL1_Q969V6-1_House_mouse_PDP.jpeg)
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