Thermo Fisher Scientific GLRX Monoclonal Antibody (28C3)
GLRX 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. ELISA 및 면역침강(IP)에 사용 가능. Jurkat 세포를 양성 대조군으로 권장. 연구용으로만 사용되며, 안정적인 액상 형태로 -20°C에서 보관.
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Thermo Fisher Scientific GLRX Monoclonal Antibody (28C3)
Applications
- ELISA (ELISA): Assay-dependent
- Immunoprecipitation (IP): 1–2 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 28C3 |
| Immunogen | Purified, recombinant, human glutaredoxin 1 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_1074677 |
Product Specific Information
A suggested positive control for this product is Jurkat cells.
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH, and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH.
First recovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues.
The active sequence (Cys-Pro-Tyr-Cys) is conserved in various species. The 12-kDa dithiol protein plays a role in reduction of mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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