Thermo Fisher Scientific GLRX Monoclonal Antibody (30A1)
GLRX 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 30A1). 인간 Glutaredoxin 1에 특이적이며 IP에 적합. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Immunoprecipitation (IP)
- Tested Dilution: 1–2 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 30A1 |
| Immunogen | Purified, recombinant, human glutaredoxin 1 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2110352 |
Product Specific Information
A suggested positive control for this product is HepG2 cells.
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH, and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH.
First recovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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