Thermo Fisher Scientific SYP Monoclonal Antibody (UMAB112), UltraMAB
인간 Synaptophysin 단백질을 인식하는 UMAB112 클론의 마우스 단클론 항체. WB, IHC, ICC, ChIP 등 다양한 실험에 사용 가능. 무보존 Lyophilized 형태로 제공되며, 고순도 친화 크로마토그래피 정제. 신경말단 및 신경내분비 종양 표지 연구용.
- 카탈로그번호
- UM500079CF
- 판매단위
- pk
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Thermo Fisher Scientific SYP Monoclonal Antibody (UMAB112), UltraMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB112 |
| Immunogen | Full-length human recombinant Synaptophysin protein (UniProt ID: P08247-1) produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein located in presynaptic vesicles of nearly all neurons. It contains four transmembrane domains and forms a complex with dynamin under high calcium conditions, suggesting a role in synaptic vesicle endocytosis.
It contributes to the regulation of short-term and long-term synaptic plasticity and serves as a widely used marker for nerve terminals and neuroendocrine tumor differentiation.
Mutations in the synaptophysin gene are associated with X-linked mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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