Thermo Fisher Scientific SYP Monoclonal Antibody (UMAB112), UltraMAB

Thermo Fisher Scientific SYP Monoclonal Antibody (UMAB112), UltraMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Synaptophysin is a calcium-binding integral membrane glycoprotein located in presynaptic vesicles of nearly all neurons. It contains four transmembrane domains and forms a complex with dynamin under high calcium conditions, suggesting a role in synaptic vesicle endocytosis.
It contributes to the regulation of short-term and long-term synaptic plasticity and serves as a widely used marker for nerve terminals and neuroendocrine tumor differentiation.
Mutations in the synaptophysin gene are associated with X-linked mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.