Thermo Fisher Scientific OSMR Polyclonal Antibody
Human OSMR 인식하는 염소 유래 Polyclonal 항체로 Western blot 및 Flow cytometry에 적합. 항원 친화 크로마토그래피로 정제되었으며 보존제 무첨가. 재구성 후 -20°C에서 보관하며 마우스 OSMR과의 교차 반응은 5% 미만.
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Thermo Fisher Scientific OSMR Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Flow Cytometry (Flow) | 0.25 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human OSM R beta (Glu28–Ser739) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605845 |
Product Specific Information
- In Western blots, less than 5% cross-reactivity with recombinant mouse OSM R beta is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Oncostatin M (OSM) is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily.
Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells.
OSMR acts as an alternative subunit forming an OSM receptor complex (heterodimer of gp130 and OSMR) activated by OSM but not by LIF.
Publication Note: This RefSeq record includes a subset of the publications available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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