Thermo Fisher Scientific NEFH Monoclonal Antibody (OTI10A7), TrueMAB
NEFH 단백질을 인식하는 마우스 단일클론 항체로, Western Blot 및 IHC(P) 실험에 적합합니다. 인간 시료에 반응하며, 동결건조 형태로 제공됩니다. 신경세포 내 중간섬유 단백질 연구 및 ALS 관련 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 778–1020 of human NEFH produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Neurofilaments are intermediate filament proteins specific to neurons, composed mainly of NF-L, NF-M, and NF-H.
NEFH (NF-H) plays a crucial role in maintaining neuronal caliber and axonal structure. Its expression is tissue-specific and developmentally regulated.
NF-H is also implicated in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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