Thermo Fisher Scientific NEFH Monoclonal Antibody (OTI7E4), TrueMAB
인간 NEFH 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도로 사용 가능. 신경세포 내 신경필라멘트 연구 및 ALS 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7E4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 778–1020 of human NEFH produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Neurofilaments are intermediate filament proteins specific to neurons, composed mainly of NF-L, NF-M, and NF-H. NF-H plays a crucial role in maintaining neuronal caliber and is involved in axonal structure and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS).
Expression of neuronal intermediate filament proteins is tissue-specific and developmentally regulated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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