Thermo Fisher Scientific Kos1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing mouse Kos1 (TNK1) protein. Suitable for Western blot applications. Supplied as a liquid at 1 mg/mL concentration. Recommended storage at 4°C short-term or -20°C long-term. For research use only.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C-terminal residues 421–434 [QNQVQSLPAGSAEP] of the 47 kDa mouse Kos1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
TNK1 (tyrosine kinase, non-receptor 1) belongs to the tyrosine protein kinase family and is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. It may function broadly in signaling pathways during fetal development and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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