Thermo Fisher Scientific NABC1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human NABC1 (BCAS1) residues 532-550. Validated for Western blot at 1:500–1:1,000 dilution. Supplied as liquid, 1 mg/mL concentration. For research use only.
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Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Residues 532–550 (DTNSLQNGDKLQKRPEKRQ) of human NABC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
BCAS1 was identified through positional cloning and found to be overexpressed in most, but not all, breast cancer cell lines. BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are observed in brain and prostate tissues, with lower amounts in colon, intestine, and testis. Overexpression of BCAS1 does not induce anchorage-independent growth, suggesting it is not a typical oncogene. Amplification of BCAS1 has also been reported in other carcinomas such as pancreatic carcinoma, indicating a potential role in cell proliferation control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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