Thermo Fisher Scientific TLE1 Monoclonal Antibody (UMAB253), UltraMAB
TLE1 단백질을 인식하는 Mouse Monoclonal 항체로, Western blot, IHC, ICC/IF, ChIP 등 다양한 응용 가능. Human 시료 반응성. 고순도 Affinity chromatography 정제. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적 유지.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:300 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB253 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 180–460 of human TLE1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transcriptional corepressor that binds to multiple transcription factors. Inhibits NF-kappa-B-regulated gene expression and transcriptional activation mediated by FOXA2, CTNNB1, and TCF family members in Wnt signaling. The function of full-length TLE family members may be modulated by association with dominant-negative AES. Also acts as an unusual coactivator for ESRRG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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