Thermo Fisher Scientific WASP Polyclonal Antibody
Rabbit polyclonal antibody recognizing human WASP protein. Validated for Western blot and ELISA applications. Supplied as a liquid, affinity-purified antibody in PBS with glycerol. Recommended storage at -20°C. For research use only.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific WASP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 60–250 of human WASP (UniProt ID: P42768-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913633 |
Product Specific Information
- Positive test controls: HL-60, THP-1, Ramos
- Subcellular localization: Cytoplasm, cytoskeleton
Immunogen sequence:
GAEHWTKEHC GAVCFVKDNP QKSYFIRLYG LQAGRLLWEQ ELYSQLVYST PTPFFHTFAG DDCQAGLNFA DEDEAQAFRA LVQEKIQKRN QRQSGDRRQL PPPPTPANEE RRGGLPPLPL HPGGDQGGPP VGPLSLGLAT VDIQNPDITS SRYRGLPAPG PSPADKKRSG KKKISKADIG APSGFKHVSH V
Target Information
The Wiskott-Aldrich syndrome family of proteins share similar domain structures and are involved in transducing signals from cell surface receptors to the actin cytoskeleton. These proteins are regulated by multiple stimuli and interact with various partners, including the small GTPase Cdc42 and the Arp2/3 complex, which regulate actin filament formation.
Wiskott-Aldrich syndrome is an X-linked recessive disorder characterized by immune dysregulation and microthrombocytopenia, caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein expressed exclusively in hematopoietic cells, which exhibit signaling and cytoskeletal abnormalities in affected individuals.
A transcript variant resulting from alternative promoter usage and containing a different 5′ UTR sequence has been described, though its full-length nature remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.