Thermo Fisher Scientific TEM7 Polyclonal Antibody
TEM7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 적합합니다. Human, Mouse, Rat 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS buffer에 0.02% sodium azide 포함, 냉장 보관 권장.
- 카탈로그번호
- PA520427
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the carboxy terminus of human TEM7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153807 |
Product Specific Information
- Suggested positive control: human liver tissue lysate
- PA5-20427 can be used with blocking peptide PEP-0544
Target Information
Using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al. identified 46 genes with expression elevated in tumor-associated endothelium. Nine of these, named Tumor Endothelial Markers (TEMs, TEM1–9), are expressed primarily in tumor endothelial cells but not in normal endothelial cells.
TEM7 transcripts are specifically expressed in the endothelium of colorectal, lung, pancreas, breast, and brain cancers, both in primary and metastatic tumors. Other family members (TEM1, 3, 4, 5, 8, and 9) show similar expression patterns in lung and brain tumors and liver metastasis.
These genes may serve as valuable resources for studying human angiogenesis in both basic and clinical research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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